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Milo Ventimiglia (of the blockbuster TV series Heroes), headlines this dark crime thriller, which marks the sophomore directorial outing of Marc Schoelermann, following the 2006 telemovie Hexxx. Ventimiglia portrays a young intern, newly arrived at the University Hospital in Philadelphia, who stumbles onto a psychopathic group of colleagues playing a vile game. They regularly select one of their members (on a rotational basis) to commit the "perfect murder," while the rest use forensic methods to try to determine exactly how the homicide was executed. Alyssa Milano (of TV's Who's the Boss? and Charmed) co-stars as Ventimiglia's fiancée, while thesps Johnny Whitworth and Lauren Lee Smith are among the perpetrators.

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Special Fatures cc Audio commentary by director Marc Schölermann and screenwriters/ producers Marc Neveldine and Brian Taylor Creating the Perfect Murder featurette The Cause of Death: A Conversation With Pathologist Craig Harvey featurette Music video: "Unintended Consequences" performed by the Legion of Doom F/Triune Extended autopsy scene

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